proton-pump inhibitor


proton-pump inhibitor
a drug that reduces gastric acid secretion by blocking the proton pump within the oxyntic (parietal) cells. Proton-pump inhibitors include esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole; they are used for treating gastric and duodenal ulcers, reflux oesophagitis, and the hypersecretion caused by gastrinoma.

The new mediacal dictionary. 2014.

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  • Proton pump inhibitor — Proton pump inhibitors (or PPI s) are a group of drugs whose main action is pronounced and long lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available today. The group followed and has… …   Wikipedia

  • proton pump inhibitor — n any of a group of drugs (as omeprazole) that inhibit the activity of proton pumps and are used to inhibit gastric acid secretion in the treatment of ulcers and gastroesophageal reflux disease abbr. PPI * * * (PPI) an agent that inhibits the… …   Medical dictionary

  • proton pump inhibitor — noun Any of several short term treatments for gastric and duodenal ulcers and for the eradication of the bacterium helicobacter pylori (abbrev PPI) • • • Main Entry: ↑proton …   Useful english dictionary

  • proton-pump inhibitor — a drug that reduces gastric acid secretion by blocking the proton pump within the oxyntic cells. Proton pump inhibitors include lansoprazole, omeprazole, and pantoprazole; they are used for treating gastric and duodenal ulcers, reflux… …   Medical dictionary

  • proton pump inhibitor — noun Date: 1983 any of a group of drugs that inhibit the activity of pumps transporting hydrogen ions across cell membranes and are used to inhibit gastric acid secretion …   New Collegiate Dictionary

  • Ингибитор Протонного Насоса (Proton-Pump Inhibitor) — лекарственное вещество, уменьшающее секрецию желудочной соляной кислоты путем блокирования протонного насоса в обкладочных (париетальных) клетках желудочных желез. К этим лекарственным веществам относится, например, омепразол; они применяются для …   Медицинские термины

  • Proton pump — This article is about proton pumps in general. For the proton P type ATPase, see proton ATPase. A proton pump is an integral membrane protein that is capable of moving protons across the membrane of a cell, mitochondrion, or other subcellular… …   Wikipedia

  • Discovery and development of proton pump inhibitors — Proton pump inhibitors (PPIs) block the gastric Hydrogen potassium ATPase (H+,K+ ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid related diseases, including gastroesophageal reflux disease… …   Wikipedia

  • gastric acid pump inhibitor — proton pump i …   Medical dictionary

  • Proton (disambiguation) — A proton is a subatomic particle with a positive fundamental electric charge of 1.6 times; 10 19 coulomb and a mass of 938 MeV in other words, a hydrogen ion, specifically 1H, which contains no neutrons.Terms derived directly from this core… …   Wikipedia


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